NC State Extension Publications

General Information

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Information on chemical plant protectants for disease control on greenhouse vegetables must be used in the context of a "Total Disease Control Program." For example, many diseases are controlled by sanitation (no smoking, fumigating soil, using disease-free seed and seedlings, removing all dead plant parts, and washing hands and equipment before moving from one house to another), use of resistant varieties, crop rotation, seed treatment, exclusion of aphids from fall crops, and cultural practices. Always use top-quality seed or plants obtained from reliable sources. Seed are ordinarily treated by the seed producer for the control of seed decay and damping-off. However, tomato seed also should be treated with Clorox to reduce the risk of tobacco mosaic virus and certain bacterial diseases.

Most foliar diseases can be reduced or controlled by maintaining relative humidity under 90%, by keeping the air circulating in the house, and watering in such a manner to avoid wetting leaves.

Spraying with fungicides should be done as to ensure coverage of all plant surfaces. We recommend the use of high-pressure and high-volume equipment or subliming products (Exotherm Termil). Application should start prior to or as soon as the disease first appears and continued on a 7- to 14-day schedule as needed. Before starting the spray schedule, be sure to obtain a diagnosis of the disease in order to use the proper material. This information may be obtained through your local N.C. Cooperative Extension center.

CAUTION: The risk of pesticide exposure in the greenhouse is high; use protective clothing laundered daily or after each exposure; ventilate house during application and use appropriate respirator. Always use the chemical as directed on the label.

Chemical Control

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Disease Product FRAC Crop Rate PHI REI
Alternaria leaf spot copper, fixed (various) M1 Basil See label See label See label
cyprodinil + fludioxinil (Switch) 9 + 12 Basil 11 to 14 oz/A 7 12h
Cucurbits (post-transplant) 11 to 14 oz/A 1 12h
Lettuce 11 to 14 oz/A 0 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Cucurbits (post-transplant) 16 to 20 fl oz/A 7 12h
famoxadone + cymoxanil (Tanos) 11 + 27 Cucurbits (post-transplant) 8 to 10 oz/A 3 12h
fludioxonil (Spirato GHN) 12 Basil 5.5 to 7 fl oz/A 7 12h
mancozeb (various) M3 Cucurbits See label See label See label
mancozeb + zoxamide (Gavel) M3 + 22 Cucurbits (post-transplant) 1.4 to 2 lb/A 5 48h
penthiopyrad (Fontelis) 7 Cucurbits (post-transplant) 0.375 to 0.5 fl oz/gal per 1,360 sq ft 1 12h
Lettuce 14 to 24 fl oz/A 3 12h
potassium bicarbonate (Milstop) NC Lettuce 1.25 to 5 lb/A 0 1h
triflumizole (Procure) 3 Lettuce 6 to 8 fl oz/A 0 12h
Angular leaf spot copper, fixed (various) M1 Cucurbits See label See label See label
Anthracnose azoxystrobin + difenoconazole (Quadris Top) 11 + 9 Tomato 8 fl oz/A 0 12h
copper, fixed (various) M1 Tomato See label See label See label
Basil See label See label See label
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Cucurbits (post-transplant) 16 to 20 fl oz/A 7 12h
Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
famoxadone + cymoxanil (Tanos) 11 + 27 Cucurbits (post-transplant) 8 to 10 oz/A 3 12h
Tomato See label 3 12h
mancozeb (various) M3 Cucurbits See label See label See label
Lettuce See label See label See label
Tomato See label See label See label
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
penthiopyrad (Fontelis) 7 Tomato 0.5 to 0.75 fl oz/gal per 1,360 sq ft 0 12h
polyoxin D zinc salt (Affirm) 19 Eggplant 6.2 oz/A 0 4h
Pepper 6.2 oz/A 0 4h
Tomato See label 0 4h
potassium bicarbonate (Milstop) NC Lettuce 1.25 to 5 lb/A 0 1h
zinc dimethyl-dithio-carbamate (Ziram) M3 Tomato 3 to 4 lb/A 7 48h
Bacterial canker famoxadone + cymoxanil (Tanos) 11 + 27 Tomato (post-transplant) See label 3 12h
Bacterial speck and spot copper, fixed (various) M1 Tomato (post-transplant) See label See label See label
famoxadone + cymoxanil (Tanos) 11 + 27 Tomato (post-transplant) See label 3 12h
mancozeb (various) M3 Tomato (post-transplant) See label See label See label
Basal rot cyprodinil + fludioxinil (Switch) 9 + 12 Lettuce 11 to 14 oz/A 0 12h
Black mold azoxystrobin + difenoconazole (Quadris Top) 11 + 9 Tomato (post-transplant) 8 fl oz/A 0 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
Botrytis copper, fixed (various) M1 Basil See label See label See label
(Botrytis blight/gray mold) cyprodinil + fludioxinil (Switch) 9 + 12 Basil 11 to 14 oz/A 7 12h
Lettuce 11 to 14 oz/A 0 12h
Tomato (post-transplant) 11 to 14 oz/A 3 12h
dicloran (Botran) 14 Lettuce See label 14 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
fenhexamid (Decree) 17 Cucurbits 1.5 lb/A or 1-1.5 lb/A if tank mixed 0 12h
Eggplant 1.5 lb/A or 1-1.5 lb/A if tank mixed See label 12h
Lettuce See label 3 12h
Pepper 1.5 lb/A or 1-1.5 lb/A if tank mixed See label 12h
Tomato (post-transplant) See label 0 12h
fludioxonil (Spirato GHN) 12 Basil 5.5 to 7 fl oz/A 7 12h
penthiopyrad (Fontelis) 7 Cucurbits (post-transplant) 0.375 to 0.5 fl oz/gal per 1,360 sq ft 1 12h
Lettuce 14 to 24 fl oz/A 3 12h
Tomato (post-transplant) 0.5 to 0.75 fl oz/gal per 1,360 sq ft 0 4h
polyoxin D zinc salt (Affirm) 19 Cucurbits See label 0 4h
Eggplant 6.2 oz/A 0 4h
Pepper 6.2 oz/A 0 4h
Tomato (post-transplant) See label 0 12h
potassium bicarbonate (Milstop) NC Lettuce 1.25 to 5 lb/A 0 12h
pyraclostrobin + boscalid (Pageant Intrinsic) 7 + 11 Tomato (post-transplant) 23 oz/A 0 12h
pyrimethanil (Scala) 9 Tomato (post-transplant) 7 fl oz/A 1 See label
Cercospora leaf spot difenoconazole + cyprodinil (Inspire Super) 3 + 9 Cucurbits (post-transplant) 16 to 20 fl oz/A 7 12h
mancozeb (various) M3 Cucurbits See label See label See label
mancozeb + zoxamide (Gavel) M3 + 22 Cucurbits (post-transplant) 1.4 to 2 lb/A 5 48h
penthiopyrad (Fontelis) 7 Lettuce 14 to 24 fl oz/A 3 12h
potassium bicarbonate (Milstop) NC Lettuce 1.25 to 5 lb/A 0 1h
Corynespora leaf spot polyoxin D zinc salt (Affirm) 19 Cucurbits See label 0 4h
Downy mildew copper, fixed (various) M1 Cucurbits See label See label See label
cyazofamid (Ranman) 21 Basil 2.75 to 3 fl oz/A 0 12h
cymoxanil (Curzate) 27 Cucurbits (post-transplant) 3.2 to 5 oz/A 3 12h
Lettuce See label See label 12h
famoxadone + cymoxanil (Tanos) 11 + 27 Cucurbits (post-transplant) 8 to 10 oz/A 3 12h
Lettuce 8 to 10 oz/A 1 12h
mancozeb (various) M3 Cucurbits See label See label See label
Lettuce See label See label See label
mancozeb + zoxamide (Gavel) M3 + 22 Cucurbits (post-transplant) 1.4 to 2 lb/A 5 48h
mandipropamid (Micora) 40 Basil 8 fl oz/A 1 4h
Cucurbits 8 fl oz/A 0 4h
Lettuce See label See label 4h
phosphorus acid (various) 33 Basil See label See label See label
potassium phosphite (various) 33 Basil See label See label See label
Drop rot dicloran (Botran) 14 Lettuce See label 14 12h
Early blight (Alternaria sp.) azoxystrobin + difenoconazole (Quadris Top) 11 + 9 Tomato (post-transplant) 8 fl oz/A 0 12h
copper, fixed (various) M1 Tomato (post-transplant) See label See label See label
cyprodinil + fludioxinil (Switch) 9 + 12 Tomato (post-transplant) 11 to 14 oz/A 3 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
famoxadone + cymoxanil (Tanos) 11 + 27 Tomato (post-transplant) See label 3 12h
mancozeb (various) M3 Tomato (post-transplant) See label See label See label
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
penthiopyrad (Fontelis) 7 Tomato (post-transplant) 0.5 to 0.75 fl oz/gal per 1,360 sq ft 0 12h
polyoxin D zinc salt (Affirm) 19 Cucurbits See label 0 4h
Eggplant 6.2 oz/A 0 4h
Pepper 6.2 oz/A 0 4h
Tomato (post-transplant) See label 0 4h
pyrimethanil (Scala) 9 Tomato (post-transplant) 7 fl oz/A 1 12h
zinc dimethyl-dithio-carbamate (Ziram) M3 Tomato (post-transplant) 3 to 4 lb/A 7 48h
Fusarium blight cyprodinil + fludioxinil (Switch) 9 + 12 Basil 11 to 14 oz/A 7 12h
Gray leaf mold copper, fixed (various) M1 Tomato (post-transplant) See label See label See label
cyprodinil + fludioxinil (Switch) 9 + 12 Tomato (post-transplant) 11 to 14 oz/A 3 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
Gray leaf spot azoxystrobin + difenoconazole (Quadris Top) 11 + 9 Tomato (post-transplant) 8 fl oz/A 0 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
mancozeb (various) M3 Tomato (post-transplant) See label See label See label
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
penthiopyrad (Fontelis) 7 Tomato (post-transplant) 0.5 to 0.75 fl oz/gal per 1,360 sq ft 0 12h
Gummy stem blight cyprodinil + fludioxinil (Switch) 9 + 12 Cucurbits (post-transplant) 11 to 14 oz/A 1 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Cucurbits (post-transplant) 16 to 20 fl oz/A 7 12h
mancozeb (various) M3 Cucurbits See label See label See label
penthiopyrad (Fontelis) 7 Cucurbits (post-transplant) 0.375 to 0.5 fl oz/gal per 1,360 sq ft 1 12h
polyoxin D zinc salt (Affirm) 19 Cucurbits See label 0 4h
Late blight copper, fixed (various) M1 Tomato (post-transplant) See label See label See label
cyazofamid (Ranman) 21 Tomato (post-transplant) See label 0 12h
cymoxanil (Curzate) 27 Tomato (post-transplant) 3.2 to 5 oz/A 3 12h
famoxadone + cymoxanil (Tanos) 11 + 27 Tomato (post-transplant) See label 3 12h
mancozeb (various) M3 Tomato (post-transplant) See label See label See label
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
Phytophthora blight cyazofamid (Ranman) 21 Tomato (post-transplant) See label 0 12h
famoxadone + cymoxanil (Tanos) 11 + 27 Cucurbits (post-transplant) 8 to 10 oz/A 3 12h
mancozeb + zoxamide (Gavel) M3 + 22 Cucurbits (post-transplant) 1.4 to 2 lb/A 5 48h
phosphorus acid (various) 33 Tomato (post-transplant) See label See label See label
propamocarb hydrochloride (Previcur Flex) 28 Cucurbits See label 2 12h
Lettuce See label 2 12h
Tomato (post-transplant) See label 5 12h
Powdery mildew azoxystrobin + difenoconazole (Quadris Top) 11 + 9 Tomato (post-transplant) 8 fl oz/A 0 12h
cyprodinil + fludioxinil (Switch) 9 + 12 Cucurbits (post-transplant) 11 to 14 oz/A 1 12h
Lettuce 11 to 14 oz/A 0 12h
Tomato (post-transplant) 11 to 14 oz/A 3 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Cucurbits (post-transplant) 16 to 20 fl oz/A 7 12h
Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
penthiopyrad (Fontelis) 7 Cucurbits (post-transplant) 0.375 to 0.5 fl oz/gal per 1,360 sq ft 1 12h
Lettuce 14 to 24 fl oz/A 3 4h
Tomato (post-transplant) 0.5 to 0.75 fl oz/gal per 1,360 sq ft 0 12h
polyoxin D zinc salt (Affirm) 19 Cucurbits See label 0 4h
Eggplant 6.2 oz/A 0 4h
Pepper 6.2 oz/A 0 4h
Tomato (post-transplant) See label 0 4h
potassium bicarbonate (Milstop) NC Cucurbits (post-transplant) 1.25 to 5 lb/100 gal 0 1h
Lettuce 1.25 to 5 lb/A 0 1h
sulfur (various) M2 Lettuce See label See label See label
Tomato (post-transplant) See label See label See label
triflumizole (Procure) 3 Lettuce 6 to 8 fl oz/A 0 12h
Pythium root rot phosphorus acid (various) 33 Basil See label See label See label
propamocarb hydrochloride (Previcur Flex) 28 Cucurbits See label 2 12h
Lettuce See label 2 12h
Tomato (post-transplant) See label 5 12h
Rhizoctonia root rot phosphorus acid (various) 33 Basil See label See label See label
Scab mancozeb (various) M3 Cucurbits See label See label See label
polyoxin D zinc salt (Affirm) 19 Cucurbits See label 0 4h
Sclerotinia rot cyprodinil + fludioxinil (Switch) 9 + 12 Lettuce 11 to 14 oz/A 0 12h
dicloran (Botran) 14 Lettuce See label 14 12h
penthiopyrad (Fontelis) 7 Cucurbits (post-transplant) 0.375 to 0.5 fl oz/gal per 1,360 sq ft 1 12h
Septoria leaf spot difenoconazole + cyprodinil (Inspire Super) 3 + 9 Cucurbits (post-transplant) 16 to 20 fl oz/A 7 12h
Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
cyprodinil + fludioxinil (Switch) 9 + 12 Lettuce 11 to 14 oz/A 0 12h
penthiopyrad (Fontelis) 7 Lettuce 14 to 24 fl oz/A 3 12h
azoxystrobin + difenoconazole (Quadris Top) 11 + 9 Tomato (post-transplant) 8 fl oz/A 0 12h
copper, fixed (various) M1 Tomato (post-transplant) See label See label See label
famoxadone + cymoxanil (Tanos) 11 + 27 Tomato (post-transplant) See label 3 12h
mancozeb (various) M3 Tomato (post-transplant) See label See label See label
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
penthiopyrad (Fontelis) 7 Tomato (post-transplant) 0.5 to 0.75 fl oz/gal per 1,360 sq ft 0 12h
zinc dimethyl-dithio-carbamate (Ziram) M3 Tomato (post-transplant) 3 to 4 lb/A 7 48h
Target spot azoxystrobin + difenoconazole (Quadris Top) 11 + 9 Tomato (post-transplant) 8 fl oz/A 0 12h
difenoconazole + cyprodinil (Inspire Super) 3 + 9 Tomato (post-transplant) 16 to 20 fl oz/A 0 12h
mandipropamid + difenoconazole (Revus Top) 3 + 40 Tomato (post-transplant) 5.5 to 7 fl oz/A 1 12h
penthiopyrad (Fontelis) 7 Tomato (post-transplant) 0.5 to 0.75 fl oz/gal per 1,360 sq ft 0 12h
Tomato (post-transplant) See label 0 12h
Watery soft rot dicloran (Botran) 14 Lettuce See label 14 12h
White rust famoxadone + cymoxanil (Tanos) 11 + 27 Lettuce 8 to 10 oz/A 1 12h

Other Links

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For assistance with a specific problem, contact your local N.C. Cooperative Extension center.

Note on Recommendations

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Recommendations of specific chemicals are based upon information on the manufacturer's label and performance in a limited number of trials. Because environmental conditions and methods of application by growers may vary widely, performance of the chemical will not always conform to the safety and pest control standards indicated by experimental data. All recommendations for pesticide use were legal at the time of publication, but the status of registration and use patterns are subject to change by actions of state and federal regulatory agencies.

Acknowledgements

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Previous versions of this factsheet were prepared by Michelle Henson, Charles Averre, S. F. Jenkins, and Paul B. Shoemaker.

Authors

Extension Associate, Vegetable and Herbaceous Ornamental Pathology
Entomology and Plant Pathology
Research Associate
Entomology & Plant Pathology

Find more information at the following NC State Extension websites:

Publication date: Dec. 6, 2017
Revised: Aug. 2, 2023

The use of brand names in this publication does not imply endorsement by NC State University or N.C. A&T State University of the products or services named nor discrimination against similar products or services not mentioned.

Recommendations for the use of agricultural chemicals are included in this publication as a convenience to the reader. The use of brand names and any mention or listing of commercial products or services in this publication does not imply endorsement by NC State University or N.C. A&T State University nor discrimination against similar products or services not mentioned. Individuals who use agricultural chemicals are responsible for ensuring that the intended use complies with current regulations and conforms to the product label. Be sure to obtain current information about usage regulations and examine a current product label before applying any chemical. For assistance, contact your local N.C. Cooperative Extension county center.

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