NC State Extension Publications


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The North Carolina Agricultural Chemicals Manual provides extension specialists and agents, researchers, and professionals in the agriculture industry with information on the selection, application, and safe and proper use of agricultural chemicals. The manual is revised annually offering a wealth of up-to-date and reliable information covering pesticides, fertilizers, application equipment, specimen identification, growth regulators, and the control of insects, diseases, weeds, and animals.

This edition was prepared by the College of Agriculture and Life Sciences at North Carolina State University and by an editorial committee consisting of Katie Jennings, Horticultural Science, Chair; Hannah J. Burrack, Entomology and Plant Pathology; Charlie Cahoon, Crop and Soil Sciences; Ramon Leon, Crop and Soil Sciences; Christopher S. DePerno, Forestry and Environmental Resources; Lina Quesada, Entomology and Plant Pathology; Matthew Vann, Crop and Soil Sciences; Jason Ward, Biological and Agricultural Engineering; Dale Monks, Administrative Advisor; and James W. Burnette Jr., Structural Pest Control & Pesticide Division, North Carolina Department of Agriculture & Consumer Services.

Printed Manual

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Copies of the current manual are available for purchase online through UNC Press.

Customers ordering five (5) or more copies are eligible for a 25% discount by applying promotion code 01NCSU25 into the shopping cart at checkout. You can also place an order by calling 800-848-6224 and using the same promotion code.

Copies of the current North Carolina Agricultural Chemicals Manual can also be purchased from the NC State Bookstore.


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Recommendations of specific chemicals are based on information on the manufacturer’s label and performance in a limited number of trials. Because environmental conditions and methods of application by growers may vary widely, performance of the chemical will not always conform to the safety and pest control standards indicated by experimental data.

Recommendations for the use of agricultural chemicals are included in this publication as a convenience to the reader. The use of brand names and any mention or listing of commercial products or services in this publication does not imply endorsement by North Carolina State University nor discrimination against similar products or services not mentioned. Individuals who use agricultural chemicals are responsible for ensuring that the intended use complies with current regulations and conforms to the product label. Be sure to obtain current information about usage regulations and examine a current product label before applying any chemical. For assistance, contact your local N.C. Cooperative Extension center. ​

Useful Phone Numbers

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NC Poison Control Center
NC Poison Control Center can give advice on diagnosis and treatment of human illness resulting from toxic substances.

NCDA&CS Structural Pest Control and Pesticides Division
The NCDA&CS Structural Pest Control and Pesticides Division provides information and help to aid in responding to emergencies involving pesticides.

National Pesticide Information Center
NPIC provides information by phone about pesticides Monday through Friday, 8 a.m. to 12 p.m., Pacific Time.

Pesticide Disposal Assistance Program
919-733-3556 (Raleigh, NC)
PDAP gives information and assistance for disposal of unwanted pesticides.

Misuse of Pesticides

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It is illegal to use any pesticide in a manner not permitted by its labeling. The status of registration and use patterns of pesticides mentioned in this manual are subject to change by actions of state and federal regulatory agencies.

Table of Contents

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Restricted Use Pesticides; Special Local Need - Active 24(c) Registrations in North Carolina; The Safe Use of Pesticides; Growth Regulators, Defoliants, Dessicants; Fumigants; Molluscicides


Introduction; Types of Equipment; Calibrating Chemical Application Equipment; Useful Tables and Data


How to Send Specimans; Plant Disease and Insect Clinic; Insect Identification; Precautions and Limitations


Lime and Fertilizer Suggestions for Field, Pasture, and Hay Crops; Fertilizer Suggestions for Tree Fruit; Fertilizer Suggestions for Small Fruit; Lime and Fertilizer Suggestions for Lawns; Fertilizer Suggestions for Ornamental Plants in Landscapes; Fertilizer Suggestions for Nursery Crops; Lime and Fertilizer Suggestions for Vegetable Crops; Fertilizer Rules and Regulations; Nutrient Content of Fertilizer Materials; Solubility of Selected Fertilizer Materials; Mixing Herbicides With Nitrogen Solutions or Fluid Fertilizers; How to Test Compatibility of Herbicides with Fluid Fertilizers; Fertilizer Placement; Livestock & Poultry Manure Production Rates and Nutrient Content; Beneficial Use of Municipal Biosolids; Certified Organic Farm Management Alternatives


Relative Toxicity of Pesticides to Honey Bees; Reducing the Risk of Pesticide Poisoning to Honey Bees; Insect Control in Field Corn; Grain Sorghum; Small Grains; and Cotton
Cotton Insect Resistance Management
Insect Control in Peanuts; Soybeans; Flue-Cured and Burley Tobacco; and Commercial Vegetables
Relative Effectiveness of Insecticides and Miticides for Insect and Mite Control on Vegetables; Preharvest Intervals for Pyrethroid Insecticides in Vegetable Crops
Insect Control for Greenhouse Vegetables
Insect Control for Livestock and Poultry; Community Pest Control; Industrial and Household Pests; Arthropod Management for Ornamental Plants Grown in Greenhouses; and Ornamental Plants Grown in Nurseries or Landscapes
Arthropod Control on Christmas Trees; Commercial Turf Insect Control; Insect Control for Wood and Wood Products; Insect Control for the Home Vegetable Garden; Control of Household Pests; Insect Control for Home Lawns; Insect Management in Industrial Hemp


Apple Spray Program; Blueberry Management Program; Caneberry Management Program; Bunch Grape Insect Management; Bunch Grape Disease Mangement; Peach and Nectarine Spray Guide; Nematode Control on Peaches; Commerical Pecan Insect Control; Commerical Pecan Insect and Spray Guide; Pecan Disease Control; Strawberry Disease Control; Strawberry Disease Control; Strawberry Insect Management


Chemical Weed Control in Field Corn; Cotton; Peanuts; Sorghum; Soybeans; Sunflowers; Tobacco; and Wheat, Barley, Oats, Rye, and Triticale
Glyphosate Formulations; Herbicide Resistance Management; Herbicide Modes of Action for Hay Crops, Pastures, Lawns and Turf
Chemical Weed Control in Clary Sage; Small Fruit Crops; Tree Fruit Crops; Hay Crops and Pastures; Lawns and Turf; Ornamentals; Vegetable Crops; and Forest Stands
Forest Site Preparation, Stand Conversion, Timber Stand Improvement; Aquatic Weed Control; Chemical Control of Specific Weeds; and Woody Plants
Total Vegetation Control on Noncropland


Growth Regulators for Cotton; Guide for Use of Defoliants on Cotton; Harvest Aids, Preharvest Desiccants, and Postharvest Desiccants; Growth-Regulating Chemicals for Apples
Growth Regulators for Floriculture Crops in Greenhouses; and Woody Ornamental Crops
Sucker Control for Flue-Cured Tobacco; Yellowing Agents for Flue-Cured Tobacco; Sucker Control for Burley Tobacco
Growth Regulators for Fruiting Vegetables; Peanuts; and Turfgrasses


Animal Damage Control; Description of Potential Animal Pests; Animal Control Suggestions; Rodenticides; Fish Control


Foliar Fungicides for Wheat Leaf Disease Control; Fungicide Efficacy for Control of Wheat Diseaseas; Seed Treatment for Wheat Foliar Disease Control; Nematode Control in Corn; Fungicides for Control of Corn Foliar Diseases; Fungicide Efficacy for Control of Corn Diseases; Cotton Disease Control; Peanut Disease Control; Peanut Disease Management Calendar; Soybean Disease Control; Relative Fungicide Efficacy for Control of Soybean Seedling Diseses; Tobacco Disease Control; Turfgrass Disease Control; Nematicides for Turf; Floral, Nursery, and Landscape Diseases; Disease Control for Forest, Christmas, and Ornamental Trees; Commerical Landscape and Nursery Crops Disease Control; Disease Control for Commerical Vegetables; Nematode Control in Vegetable Cops; Fumigants; Management of Soilborne Nematodes with Non-Fumigant Nematicides; Greenhouse Vegetable Crop Disease Control; Seed Treatments; Sanitation; Various and Alternative Fungicides; Fungicide Resistance Management


North Carolina State University

Publication date: Feb. 23, 2022

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