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Grapes grown in North Carolina are sometimes exposed to unfavorable climatic conditions and biological pests that can reduce crops and injure or kill grapevines. Climatic threats include low winter temperatures, late spring frosts, excessive summer heat, and unpredictable precipitation. Biological pests include fungal pathogens and insects that attack the foliage and fruit of vines, as well as birds, deer, and other wildlife that consume fruit and shoots.Vineyard site selection greatly affects both the frequency and severity of these problems and is one of the most important factors affecting profitability in viticulture.