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Tomato pith necrosis, first observed on tomato plants in 1978, continues to be a threat to tomato production across the US. The disease most severely impacts crops where high humidity and stress conditions are present, and as a result, it is mostly a concern for greenhouse and high tunnel tomatoes, but it can also impact field-grown tomatoes. There are currently no tomato varieties resistant to pith necrosis, nor any chemical treatments commercially available, so preventing the disease with good management practices is the best way to limit its occurrence.