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Grapes are subject to attack by many different pests, including nematodes, fungal, bacterial, and viral pathogens, insects, and wildlife, such as deer and birds.Weeds, which compete with the vines for soil moisture and nutrients, may also be included in this list. Recognizing and understanding the nature of these pests is essential to minimizing crop losses.This chapter briefly describes the major pests that routinely threaten bunch grapes in North Carolina and discusses control measures.